Vivonoetics, in partnership with Great Lakes NeuroTechnologies, will be providing advanced respiratory assessment to the Roche FIREFISH study. It will be the first large SMA-1 clinical trial to use Respiratory Inductance Plethysmography (RP) systems to non-invasively sense respiratory excursions of the body. By measuring and analyzing the precise patterns of movement of both the chest and abdominal wall, objective measures of pulmonary function may be appropriately evaluated. Specialty analysis of RP data for the evaluation of infant breathing is possible using Vivonoetics’ proprietary VivoSense analysis software together with trained data analysts. RP sensing technology will be provided using the BioRadio from Great Lakes NeuroTechnologies, a wireless, wearable data acquisition system capable of recording RP on infants in real time. RP data are wirelessly transmitted to a computer via Bluetooth and made available to the Vivonoetics analytics team for post-collection processing and analysis.