Boston’s Brigham and Women’s Hospital and Evidation Health will test Medisafe’s medication adherence app in a randomized control trial of 390 patients taking medication for high blood pressure. Patients will be monitored with an at-home Bluetooth blood pressure cuff.

Medisafe’s app includes medication reminders, an educational newsfeed, and social support from friends. Although it has demonstrated some impressive results in previous studies, Medisafe data wasn’t randomized, and that’s where this latest study kicks in.

“In … previous studies where Medisafe has shown there is some evidence that their app is helpful, those are patients that already had the goal of trying out the app to help them. So after they use the app, they have a tool to get them there,” Dr. Kyle Murowski, a fellow in implementation research at the Brigham and Women’s Center for Healthcare Delivery Sciences and one of the lead investigators on the study, told MobiHealthNews. “But the question is ‘would they have gotten there anyway?’ Would they already have had their blood pressure controlled without the app? That’s the question that remains this side of randomization. Once randomization happens and you can compare two groups, and you can hard and fast say ‘the technology is providing the medication control.'”

Evidation Health on its end will be managing the logistics of providing patients with the blood pressure monitors and provide them with training how to use these devices.

The principal investigator on the study is Niteesh Choudhry, who presided over a famous 2011 trial called MI FREEE (Post-Myocardial Infarction Free Rx Event and Economic Evaluation) which studied the effects of free medications on heart attack rates.